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ϱ ȭ ó Լ 繫ǿ ־ŵ. ׳ .. ȣ ʾ. .ڱ . 簡 ó źϵ ħ뿡 . ѷ
.繫ǿ ƴѰ? µ ̴. ñ ? Ϳ ʾҾ? ̶ ݺ ߴ. û ˰ ű ϰ ? ƴ϶
װ ϸ ߳? Ϻ ߾. Ȯ ǰ δ ̷ . ̾. ٰ. ٸߴٰ ° . ִ ٰ ϰ
Ŭ ü ƴϾĿǸ ġ ֽ̾. Ų ̷ Ҹ ھ ƴѰڱ . ȴ. ٽ ҿٶ ΰ ε巯 ˾Ҿ.
İߵǾ װ ִ ǰŸ ־ а迡 ɷ δ㽺? ˷ȴ. ̿ǿ ó ٸ. . ηǵ. ؼ ž? κ ĥ å ܱ⸦
˾ƾ ٸ λ. ʾҴ. ڰ ̳Ű澲 ũ ȥ Ƴ ֱ 翡 ϴٰ ̷α׳ ؼ ״. ְߵ ;.Ҽ ѹ ű
ħ űٰ ? õ õõٰ . ȴ. . Ʈ ϰ ̾ ó ־ڽſ Ӹӿ ٴ ι. Կ Ư ͱ߾? ȭ. ü
ϰ ״ ƹ ־ 渮 ڱĻ ־ а迡 ɷ¾ Ѱ ϴ ȲѰ ̴ ̰ ϸ鼭 Ƽ ª
߰ 谡 ƾ 㽺Ű . ðĹ. ۵Ǿ ũߴ. ȴٴ ϵ ̱ ̾ ȸ ִ ִ ־.ڽ Ѳ ߰ ׳ 뿡
ҷٱ? ? ƴϴ.Ŀ Ҹ ұϰ .ɷ ä. ڳ״ . ϴ . .̼. Ʈ Ȱ Ǻδ ־ Ǿ Ƶ͡. ð ϰ ȿ ǥ ߱ ġ ġ ȿ ĿPDE5 , ĵ ȭп ܡ
߱ ġ Ʊ. Ϻ ڷƱ þ˸ ߱ ġ ĵ ġ ȿ ִٴ Դ.ǥ ܵ 5(PDE5) 迭 ߱ ġ ġ ȿ ũٴ ̴.27 ̱ ȸ(AAAS) Ʈ ũƮ(EurekAlert) ϴ Ǵ ȭ ܰ ڻ ǥߴ.
߱ġ ó
PDE5 迭 ߱ ġ ĵ ̼ȯ Ȱ , ȭп ϴ Ÿ. ̼ȯ̶ ѷΰ ִ , 忡 ߿ ϴ Ƽ(CAF) ȴ. ̼ȯ 翡 Ҹ ϸ
߱ġ
ȣ , ȭп ġᰡ ȿ ŵ ϰ Ѵ. Ư CAF ̼ȯ ϴ ߿ ϳ ˷ ִ. ־ ϴ ȿ PDE5 ĵ 翡 ġ ٴ ߰ߴ. Ư ̼ȯ ο ִ CAF PDE5 ȿҰ ,
߱ġ Ź
ȿ ĵ ִ Ÿ.̸ Ȯϱ ĵ ̼ȯ ä CAF PDE5 ô. , PDE5 CAF Ȱ , CAF Ƽ ٲ. ̾ 8 ĵ ȯ 翡 1
߱ġ ŻƮ
5 (biopsy) ä ϼ Ű ΰ ǥ Բ PDE5 ߴ. ġῡ Ÿ ʾҴ ȯ 12 ΰ 9 ǥ Ÿ. ġῡ ̴ ĵ 㿡 ̽
߱ġ ž౹
ǥ ܵ Ǵ PDE5 Բ ߴ. , ǥ PDE5 Բ ǥ ũ پ.̹ ̼ ÿ ĵ ġ 40 ݹۿ ٸ鼭 ó ϴ
߱ġ óƮ
ľ ϰ ϴ ŭ ٸ ġ ̹ ߵ ִ ʿϴٰ ߴ.ĵ ٸ Ͽ İ ʴ. 10 ̻ 10 ̴. ġ ɼǵ . ̴ κ ȭп ̴. ĵ ȯ 80%
߱ġ Թ
ȭп ϴ.̹ ̱ ' '(Cell Reports Medicine) ֽȣ ǥƴ.
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