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    彺̴ǰ 99 ĬŸ ǵ Ʈ꿰 ǰ ߱ġ ۿ ¶ ó ° ˸ǸóƮ λ Ʊ׶ Ǹ ǰ Ǹ Ʈ Ի̱ 20mg Ʊ׶ Spanish fly ȿ ī ׶ 1ڽ ɰ ǰ óƮ ɰ ̱ǰƮ ó þ˸ 20mg ı ƮѾ˹ ¶ ɰ ¶ Ź ߱ġ ǸŻƮ Ի̱Ʈ Ʊ׶ Ⱦƿ ߱ġȿ Ʈ Ʊ׶ ͳ ˸ Ǹ ǰ ˸ Ʈ ǰ ߱ġ ȿ ǰī׶Ĵ° s ̱ǰ Ʊ׶ ȿ Ϻ Ͱ ǰ ǰ GHB ͳ Ʈ Ǹó ˸ ϴ° 伺ȮϹ ٸ Ʊ׶ũ þ˸ ǰ ͳ ˸Ǹó ͳ ó þ˸ ó þ˸ ǰ ǰ ¶ ߱ġǸ þ˸5mg ǰڹ ۿ ˸ ĺ Ʊ׶ ۿ ǰ ǰ Ǹó ǰ þ˸ŻƮ ǰ Ʈ󱸸ŻƮ Ʊ׶ þ˸ þ˸ ¶ Ź 彺̴ þ˸ þ˸ ۿ Ͻö Ʊ׶ ۿ þ˸Ǹ Ʈ þ˸ þ˸ Ǹ ߱ġ Ǹ Ʈ ౹Ǹ ɰԾ౹ ¶ Ǹ ǰ þ˸ ȿ 彺̴ ǰڹ ڹ ǰ ˸ Ʈ ׸ ͱó Ʈ ǰ Ʊ׶ ڽƽ ౹ ó Ի̱Ʊ׶ ó޴¹ ǰ ԻƮ ˸ ȿ ԻƮ ǰ Ǹó ʸ þ˸ ͳ Ʈ Ʈ ͳ ߱ġó ǸóƮ ǰ ɰ Ʈó ˸Թ ͳ GHB Ʈ Թ þ˸ ¶ ó ü ǰ ߱ġ Ʈ Ⱦƿ ƮϹ GHB ȿ õ߱ ͳ ˸ Թ Ʊ׶Ϲ ڹó ghb Ǹ ¶ Ǹó ¶ Թ ߱ġ ó ϴ° Թ ¶ GHBǸó Ʈ󱸸ŻƮ ͳ ɰ Թ ó ڽϹ



    ׿ ϱ ȭ ó Լ 繫ǿ ־ŵ. ׳ .. ȣ ʾ.  .ڱ . 簡 ó źϵ ħ뿡׵ . ѷ
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    װ ϸ ߳? Ϻ ߾. Ȯ ׷ ǰ δ ̷ . ̾. ٰ. ٸߴٰ 򰡿 ° . ִ ٰ ϰ
    Ŭ ü ƴϾĿǸ ׸ ġ ֽ̾. Ų ̷ Ҹ ھ ƴѰڱ . ȴ. ٽ ҿٶ ΰ ε巯 ˾Ҿ.
    İߵǾ װ ִ ǰŸ 󸶳 ־ а迡 ɷ δ㽺? ˷ȴ. ̿ǿ ó ٸ. . ηǵ. ؼ ž? κ ĥ å ܱ⸦
    ˾ƾ ٸ λ. ʾҴ. ڰ ̳Ű澲 ũ ȥ ޾Ƴ ֱ 翡 ϴٰ ̷α׳ ؼ ׵ ״. ְߵ ;.Ҽ ѹ ű
    ħ űٰ ? õ õõ׷ٰ . ȴ. . Ʈ ϰ ̾ ó ־ڽſ Ӹӿ ٴ ι. Կ Ư ͱ߾? ޸ ȭ. ü
    ϰ ״ ԰ ƹ ־ 渮 ڱĻ 󸶳 ־ а迡 ɷ¾󸶳 Ѱ ϴ ȲѰ ̴ ̰ ϸ鼭 Ƽ ª
    ߰ 谡 ƾ 㽺Ű . ðĹ. ׸ ۵Ǿ ũߴ. ȴٴ ϵ ̱ ̾ ȸ ִ ִ ־.ڽ ׵ Ѳ ߰ ׳ 뿡
    ҷٱ? ? ƴϴ.Ŀ Ҹ ұϰ .ɷ 𿡴ä. ڳ״ . ϴ . .̼. Ʈ Ȱ Ǻδ ־ Ǿ ޾Ƶ͡. ð 󿡼 ϰ ȿ ǥ ׾߱ ġ ġ ȿ ĿPDE5 , ĵ ׾ ȭп ܡ



    ߱ ġ Ʊ׶. Ϻ ڷƱ׶ þ˸ ߱ ġ ĵ ׾ġ ȿ ִٴ Դ.ǥ ׾ ܵ 𿡽׶5(PDE5) 迭 ߱ ġ ġ ȿ ũٴ ̴.27 ̱ ȸ(AAAS) Ʈ ũƮ(EurekAlert) ϴ Ǵ ȭ ܰ ڻ ǥߴ.
    ߱ġ ó
    PDE5 迭 ߱ ġ ĵ ̼ȯ Ȱ , ׾ ȭп ϴ Ÿ. ̼ȯ̶ ѷΰ ִ , 忡 ߿ ϴ Ƽ(CAF) ȴ. ̼ȯ 翡 Ҹ ϸ ߱ġ
    ȣ , ׾ ȭп ġᰡ ȿ ŵ ϰ Ѵ. Ư CAF ̼ȯ ϴ ߿ ϳ ˷ ִ. ־ ϴ ȿ PDE5 ĵ 翡 ġ ٴ ߰ߴ. Ư ̼ȯ ο ִ CAF PDE5 ȿҰ , ߱ġ Ź
    ȿ ĵ ִ Ÿ.̸ Ȯϱ ĵ ̼ȯ ä CAF PDE5 ô. , PDE5 CAF Ȱ , CAF Ƽ ٲ. ̾ 8 ĵ ȯ 翡 1߱ġ ŻƮ
    5 (biopsy) ä ϼ Ű ΰ ǥ ׾ Բ PDE5 ߴ.׷ ׾ ġῡ Ÿ ʾҴ ȯ 12 ΰ 9 ǥ ׾ Ÿ. ׾ ġῡ ̴ ĵ 㿡 ̽ ߱ġ ž౹
    ǥ ׾ ܵ Ǵ PDE5 Բ ߴ. , ǥ ׾ PDE5 Բ ǥ ׾ ũ پ.̹ ̼ ÿ ĵ ġ 40 ݹۿ ٸ鼭 ó ׾ ϴ ߱ġ óƮ
    ľ ϰ ϴ ŭ ٸ ġ ̹ ߵ ִ ʿϴٰ ߴ.ĵ ٸ Ͽ İ ʴ. 10 ̻ 10 ̴. ġ ɼǵ . ̴ κ ׾ ȭп ̴. ĵ ȯ 80%߱ġ Թ
    ׾ ȭп ϴ.̹ ̱ ' '(Cell Reports Medicine) ֽȣ ǥƴ.
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